Purpose
Biochemistry is often perceived as dense and disconnected from clinical practice, making it difficult for undergraduate medical students to retain and apply concepts meaningfully. Daily SPARK (Study Points for Application, Reasoning, and Key Concepts) was developed as a six-panel comic-based microlearning initiative to foster conceptual understanding, emotional engagement, and clinical relevance in biochemistry education.

Methods
Daily SPARK is an AI-assisted comic series, with scripts generated using ChatGPT and reviewed by faculty experts in biochemistry. Each comic presents a clinical or conceptual dilemma involving animated student-doctor characters. Over a 8-week period, 56 comics were disseminated to 150 first year MBBS students via WhatsApp everyday. CBME topics were covered in the DAILY SPARK. Learner perceptions were evaluated using a 5-point Likert scale survey, and reflective feedback was collected qualitatively to explore narrative impact.

Results
Survey responses from 142 students showed that 96% agreed or strongly agreed that Daily SPARK made biochemistry more approachable. Over 90% reported improved retention and greater interest in revisiting complex concepts. Reflective feedback revealed recurring themes such as “easy to recall in exams,” “connected classroom topics with real cases,” and “studying felt fun again.” The comics also encouraged peer discussion and self-directed revision. Students consistently praised the daily format, relatable characters, and the ability to grasp one concept at a time through storytelling.

Conclusion
Daily SPARK shows strong potential as a creative and effective microlearning tool in medical biochemistry. By blending clinical relevance, humor, and narrative structure, it humanizes complex content and promotes deeper engagement. This AI-assisted comic strategy can be integrated into routine teaching to enrich traditional approaches and support active recall.