Purpose: Sex and gender-based medicine (SGBM) incorporates knowledge of a patient’s sex and gender into medical decision-making and is an essential component of patient-focused, precision care. However, the majority of medical schools do not incorporate SGBM across the curriculum. The American Medical Women’s Association Sex and Gender Health Collaborative (AMWA-SGHC) connects students and healthcare experts to create free SGBM educational resources. Methods: Pre-medical and medical students from across the nation can develop one-page factsheets and/or ScholarRx Bricks (online modules) that focus on SGBM within a specific healthcare topic. To create educational materials, students are put into teams, ensuring that at least one member has clinical experience. Teams perform an in-depth literature review, create a draft, and meet with an assigned SGBM expert mentor for several rounds of revisions. Results: Since 2022, over 300 students have contributed to either a factsheet or Brick, with support from 34 topic experts. There are currently 79 medical topics being developed into a factsheet, with 8 published on the AMWA-SGHC website. Three Bricks are published on the ScholarRx platform, with 9 under development. Based on 2022-2024 data of over 200 participant students, 94% stated their SGBM knowledge increased after researching their assigned topic. Cognitive interviews conducted with five medical students revealed that they felt more prepared to share SGBM information after reviewing factsheets. Conclusions: AMWA-SGHC has developed a successful framework for mentoring trainees to create SGBM-based resources across a variety of topics. Some factsheets have been developed with interprofessional collaborations, including oral health and pharmacotherapy, expanding the applicability of our resources. Future work includes evaluating factsheets and Bricks for their efficacy in teaching SGBM-related medical knowledge in both pre-clinical and clinical settings.