The behavioral and social sciences have recently witnessed a proliferation of big team science: collaborations wherein an unusually large number of researchers pool resources in pursuit of a common goal. This movement has subsequently inspired the growth of scientific organizations dedicated to developing infrastructure, workflows, and knowledge necessary to complete large, distributed, collaborative projects in psychology. For example, the first ManyBabies project collected data from over 2,300 infants in 69 developmental psychology labs located in 16 countries around the world. Similarly, the Psychological Science Accelerator recently completed a global project examining the effects of a brief cognitive reappraisal intervention on emotional well-being during COVID-19 – a project which involved over 400 collaborators and 20,000 participants from 80+ countries. This panel discussion brings together representatives from the ManyBabies Consortium and Psychological Science Accelerator [additional panelist(s) TBD] to discuss the promises, pitfalls, and barriers they’ve encountered in the realm of big team science. This will include discussions of: decision-making and workflows; funding and sustainability; fairly incentivizing and acknowledging diverse contributions; failures and mistakes; equity, diversity, & inclusion; and navigating ethics/privacy concerns across world regions.