Purpose
In the rapidly evolving landscape of healthcare, ethical practice remains a cornerstone of professional excellence. While Entrustable Professional Activities (EPAs) are widely recognized as an effective framework for clinical competence, most students are not aware of how EPAs can be adapted to bioethics education to bridge the gap between theoretical understanding and practical application, leaving them underprepared for the ethical challenges inherent in clinical practice.

Methods
In this mixed-method study, an interactive module for EPA in Bioethics was developed and validated by group of 10 experts in Bioethics. Validation metrics included face validity, content validity using Item Content Validity Index (I-CVI) and Scale Content Validity Index (S-CVI/UA), and reliability using the Intraclass Correlation Coefficient (ICC). The module was piloted with 24 final-year medical students. Knowledge attitudes and confidence regarding EPA was assessed before and after the module implementation. Also, semi-structured in-depth small-group interviews were conducted to gauge students’ experiences and feedback.

Results
The module demonstrated strong validation outcomes. Face validity achieved an average expert-evaluation score of 4.8/5, indicating high clarity and relevance. I-CVI score was 0.990 and S-CVI/UA score was 0.992, demonstrating excellent content validity. Reliability was confirmed with an ICC value of 0.91, reflecting strong consistency among expert evaluations. After pilot implementation, students exhibited statistically significant improvements in knowledge, attitudes, and confidence in addressing ethical challenges (p < 0.0001). Qualitative feedback from students highlighted the interactive and practical nature of the module as instrumental in enhancing their understanding and readiness to apply bioethical principles in clinical settings.

Conclusions
This study highlights the effectiveness of integrating EPAs into bioethics education and enhancing students' knowledge, attitudes and confidence regarding EPAs in bioethics through a validated and interactive module. Future work should focus on expanding the scope of the module to diverse educational settings and evaluating long-term impacts on clinical practice.