Traditional physiology education often relies on static diagrams and theoretical instruction, limiting student engagement and comprehension. Advances in high-resolution physiological simulations, such as AIBODY, offer a transformative approach by enabling interactive, real-time modeling of complex biological processes. This presentation explores how simulation-based learning enhances conceptual understanding, fosters critical thinking, and bridges the gap between theoretical knowledge and clinical application. Case studies from large-scale university implementations highlight the impact on student engagement, retention, and assessment outcomes. Educators can create immersive learning experiences that elevate physiology education beyond the textbook by integrating simulation into curricula.