Age-Friendly Health Systems is an initiative of The John A Hartford Foundation and the Institute for Healthcare Improvement (IHI) in partnership witht he Americn Hospital Association (AHA) and the Catholic Health Association of the United States (CHA). The goal of the initiative is to rapidly spread the 4Ms Framework to 20 percent of the US hospitals and medical practices 2020. An Age-Friendly Health System is one in which every older adult's care: Is guided by an essential set of evidence-based practices (the 4Ms) Causes no harms, and Is Consistent with What Matters to the older adult and their family Four essential elements comprise the "4Ms" Framework of an Age-Friendly Health System: What Matters: know and align care with each older adult's specific health outcome goals and care preferences including, but not limited to, end-of-life care, and across the settings of care Medication: If medication is necessary, use Age-Friendly medications that do not interfere with What Matters to the older adult, Mobility, or Mentation across settings of care Mentation: Prevent, identify, treat, and manage dementia, depression and delirium across settings of care. Mobility: Ensure that older adults move safely every day in order to maintain function and do What Matters. The Medical University of South Carolina (MUSC) has joined this national initiative, and it participating in the ongoing second Action Community with health systems from across the country. The speaker will share information about the initiative itself, and describe our work to date, including both early successes and challenges. He will place an emphasis on strategies for health systems that may not have robust geriatrics programs in place, but that are committed to improving care for older adults throughout their system.