This 3-hour, in-person workshop will begin with an interactive group discussion to identify key barriers to designing and implementing instruction that promotes effective cognitive integration and transfer in the classroom. Following a brief review of the literature on concept-based learning and knowledge organization, cognitive integration and collaborative teaching, participants will engage in hands-on activities to collaboratively develop classroom activities that utilize Integrated Illness Scripts and Mechanisms of Disease Maps to develop the content for an Integrated Learning Session (ILS) for a pre-clerkship course. Participants will design an ILS using a template designed to compare and contrast the underlying concepts and mechanisms that underpin a variety of clinical features in related and disparate clinical conditions and inform safe clinical decision-making. Participants will then practice using these tools in the design of learning activities within their own curricular frameworks and across various educational settings (e.g., longitudinal clerkships, clerkship didactics, bedside teaching, active classrooms, faculty development). Concrete examples of the use of the tools described across several schools and various educational settings will be provided. Throughout the workshop, participants will have the opportunity to work collaboratively with their peers from other institutions to facilitate creative and shared problem-solving. Small groups will be used to ensure a high degree of interaction, and facilitators will be available to help with questions and guide discussion.